Ulmus parvifolia Modulates Platelet Functions and Inhibits Thrombus Formation by Regulating Integrin αIIbβ3 and cAMP Signaling

BackgroundThe prevalence of cardiovascular diseases (CVDs) is increasing at a high rate, and the available treatment options, sometimes, have complications which necessitates the need to develop safer and efficacious approaches. Ethnomedicinal applications reportedly reduce CVD risk. Ulmus parvifoli...

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Main Authors: Muhammad Irfan, Hyuk-Woo Kwon, Dong-Ha Lee, Jung-Hae Shin, Heung Joo Yuk, Dong-Seon Kim, Seung-Bok Hong, Sung-Dae Kim, Man Hee Rhee
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
Colecção:Frontiers in Pharmacology
Assuntos:
U. parvifolia
ethnomedicine
platelet
integrin αIIbβ3
cyclic-AMP
VASPser157
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2020.00698/full
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