Absence of ligands bound to glycoprotein IIB-IIIA on the exposed surface of a thrombus may limit thrombus growth in flowing blood.

We examined the distribution of glycoprotein IIb-IIIa (GPIIb-IIIa) and its ligands fibrinogen and von Willebrand factor (vWf) on platelets which had adhered under flow conditions. Immunoelectron microscopy was performed on whole mounts and frozen thin sections of adhering platelets. GPIIb-IIIa was h...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Heynen, H F, Lozano Molero, M, de Groot, P G, Nieuwenhuis, H K, Sixma, J J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8083351/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117425
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