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High-throughput binding affinity calculations at extreme scales
Abstract Background Resistance to chemotherapy and molecularly targeted therapies is a major factor in limiting the effectiveness of cancer treatment. In many cases, resistance can be linked to genetic changes in target proteins, either pre-existing or evolutionarily selected during treatment. Key t...
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| 主要な著者: | , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BMC
2018-12-01
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| シリーズ: | BMC Bioinformatics |
| オンライン･アクセス: | http://link.springer.com/article/10.1186/s12859-018-2506-6 |
| タグ: |
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