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Rapid and accurate ranking of binding affinities of epidermal growth factor receptor sequences with selected lung cancer drugs
The epidermal growth factor receptor (EGFR) is a major target for drugs in treating lung carcinoma. Mutations in the tyrosine kinase domain of EGFR commonly arise in human cancers, which can cause drug sensitivity or resistance by influencing the relative strengths of drug and ATP-binding. In this s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3119879/ https://ncbi.nlm.nih.gov/pubmed/21227963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2010.0609 |
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