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Rapid, accurate, precise and reproducible ligand–protein binding free energy prediction

A central quantity of interest in molecular biology and medicine is the free energy of binding of a molecule to a target biomacromolecule. Until recently, the accurate prediction of binding affinity had been widely regarded as out of reach of theoretical methods owing to the lack of reproducibility...

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Detalhes bibliográficos
Publicado no:Interface Focus
Main Authors: Wan, Shunzhou, Bhati, Agastya P., Zasada, Stefan J., Coveney, Peter V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653346/
https://ncbi.nlm.nih.gov/pubmed/33178418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2020.0007
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