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Novel Tetra-Primer ARMS-PCR Assays for Thiopurine Intolerance Susceptibility Mutations NUDT15 c.415C>T and TPMT c.719A>G (TPMT*3C) in East Asians

Thiopurines are clinically useful in the management of diverse immunological and malignant conditions. Nevertheless, these purine analogues can cause lethal myelosuppression, which may be prevented by prospective testing for variants in the thiopurine S-methyltransferase (TPMT) and, in East Asians,...

詳細記述

保存先:
書誌詳細
主要な著者: Chi-Chun Ho, Wai-Ying Fong, Yuen-Hon Lee, Wing-Tat Poon
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2017-10-01
シリーズ:Genes
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4425/8/10/285
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