Serum vascular endothelial growth factor (VEGF), soluble VEGF receptor-1 (sVEGFR-1) and sVEGFR-2 in systemic sclerosis patients: Relation to clinical manifestations and capillaroscopy findings

Introduction: The role of angiogenesis in the pathogenesis of systemic sclerosis (SSc) is well known. The imbalance between vascular endothelial growth factor (VEGF) and their anti-angiogenic soluble receptors (sVEGFR-1 and VEGFR-2) has been proposed as a possible cause of microangiopathy. Aim of th...

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Autori principali: Saeedeh Shenavandeh, Taraneh Tarakemeh, Eskandar Kamali Sarvestani, Mohammad Ali Nazarinia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017-01-01
Serie:Egyptian Rheumatologist
Soggetti:
Systemic sclerosis
Vascular endothelial growth factor
Angiogenesis
Antiangiogenic factors
Modified Rodnan skin score
Accesso online:http://www.sciencedirect.com/science/article/pii/S1110116416300072
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