Prognostic and predictive value of VEGF, sVEGFR-2 and CEA in mCRC studies comparing cediranib, bevacizumab and chemotherapy

BACKGROUND: The prognostic/predictive value of potential vascular endothelial growth factor (VEGF) signalling biomarkers was evaluated retrospectively using samples from two randomized Phase III studies (HORIZON II and III) investigating cediranib in metastatic colorectal cancer (mCRC). METHODS: Bas...

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Detalhes bibliográficos
Main Authors: Jürgensmeier, J M, Schmoll, H-J, Robertson, J D, Brooks, L, Taboada, M, Morgan, S R, Wilson, D, Hoff, P M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619270/
https://ncbi.nlm.nih.gov/pubmed/23449351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.79
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