Kindlin-2 promotes Src-mediated tyrosine phosphorylation of androgen receptor and contributes to breast cancer progression

Abstract Androgen receptor (AR) signaling plays important roles in breast cancer progression. We show here that Kindlin-2, a focal adhesion protein, is critically involved in the promotion of AR signaling and breast cancer progression. Kindlin-2 physically associates with AR and Src through its two...

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Main Authors: Luyao Ma, Yeteng Tian, Tao Qian, Wenjun Li, Chengmin Liu, Bizhu Chu, Qian Kong, Renwei Cai, Panzhu Bai, Lisha Ma, Yi Deng, Ruijun Tian, Chuanyue Wu, Ying Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2022-05-01
Colecção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-022-04945-z
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