Identification of a Cryptic Bacterial Promoter in Mouse (mdr1a) P-Glycoprotein cDNA.

The efflux transporter P-glycoprotein (P-gp) is an important mediator of various pharmacokinetic parameters, being expressed at numerous physiological barriers and also in multidrug-resistant cancer cells. Molecular cloning of homologous cDNAs is an important tool for the characterization of functio...

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Main Authors: Kristen M Pluchino, Dominic Esposito, Janna K Moen, Matthew D Hall, James P Madigan, Suneet Shukla, Lauren V Procter, Vanessa E Wall, Thomas D Schneider, Ian Pringle, Suresh V Ambudkar, Deborah R Gill, Steven C Hyde, Michael M Gottesman
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4550409?pdf=render
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