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B4G2 Induces Mitochondrial Apoptosis by the ROS-Mediated Opening of Ca2+-Dependent Permeability Transition Pores
Background/Aims: Hepatocellular carcinoma (HCC) is the most common type of liver cancer. At present, only sorafenib is approved to treat HCC. In this study, we found that a 23-hydroxybetulinic acid derivative, B4G2, exhibited potent antiproliferative activity in HCC cell lines. Methods: We used four...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Cell Physiol Biochem Press GmbH & Co KG
2015-09-01
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| Σειρά: | Cellular Physiology and Biochemistry |
| Θέματα: | |
| Διαθέσιμο Online: | http://www.karger.com/Article/FullText/430212 |
| Ετικέτες: |
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