NMR Characterization of Conformational Interconversions of Lys48-Linked Ubiquitin Chains

Ubiquitin (Ub) molecules can be enzymatically connected through a specific isopeptide linkage, thereby mediating various cellular processes by binding to Ub-interacting proteins through their hydrophobic surfaces. The Lys48-linked Ub chains, which serve as tags for proteasomal degradation, undergo c...

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Hauptverfasser: Methanee Hiranyakorn, Saeko Yanaka, Tadashi Satoh, Thunchanok Wilasri, Benchawan Jityuti, Maho Yagi-Utsumi, Koichi Kato
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-07-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
Lys48-linked ubiquitin chains
NMR
multidomain protein
cyclic protein
Online Zugang:https://www.mdpi.com/1422-0067/21/15/5351
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