Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank

Abstract Background The Taiwan Human Disease iPSC Service Consortium was established to accelerate Taiwan’s growing stem cell research initiatives and provide a platform for researchers interested in utilizing induced pluripotent stem cell (iPSC) technology. The consortium has generated and characte...

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Main Authors: Ching-Ying Huang, Ling-Hui Li, Wan-Tseng Hsu, Yu-Che Cheng, Martin W. Nicholson, Chun-Lin Liu, Chien-Yu Ting, Hui-Wen Ko, Shih-Han Syu, Cheng-Hao Wen, Zhuge Yan, Hsiang-Po Huang, Hong-Lin Su, Po-Min Chiang, Chia-Ning Shen, Hsin-Fu Chen, B. Lin Ju Yen, Huai-En Lu, Shiaw-Min Hwang, Shih-Hwa Chiou, Hong-Nerng Ho, Jer-Yuarn Wu, Timothy J. Kamp, Joseph C. Wu, Patrick C. H. Hsieh
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2020-09-01
Colecção:Journal of Biomedical Science
Assuntos:
Human induced pluripotent stem cell
Cell differentiation
Stem cell bank
Drug screening
Copy number variant
Hotspot
Acesso em linha:http://link.springer.com/article/10.1186/s12929-020-00682-7
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