The β-Lactamase Inhibitor Boronic Acid Derivative SM23 as a New Anti-Pseudomonas aeruginosa Biofilm

Pseudomonas aeruginosa is a Gram-negative nosocomial pathogen, often causative agent of severe device-related infections, given its great capacity to form biofilm. P. aeruginosa finely regulates the expression of numerous virulence factors, including biofilm production, by Quorum Sensing (QS), a cel...

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Bibliografiske detaljer
Main Authors: Samuele Peppoloni, Eva Pericolini, Bruna Colombari, Diego Pinetti, Claudio Cermelli, Francesco Fini, Fabio Prati, Emilia Caselli, Elisabetta Blasi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-02-01
Serier:Frontiers in Microbiology
Fag:
boronic acids
Pseudomonas aeruginosa biofilm
quorum sensing
virulence factors
inhibitors
Online adgang:https://www.frontiersin.org/article/10.3389/fmicb.2020.00035/full
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