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A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes.

Circumsporozoite protein (CSP) is the dominant protein on the surface of Plasmodium sporozoites and plays a critical role in the invasion by sporozoites of hepatocytes. Contacts between CSP and heparin sulfate proteoglycans (HSPGs) lead to the attachment of sporozoites to hepatocytes and trigger sig...

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Библиографические подробности
Главные авторы: Jinghua Zhao, Purnima Bhanot, Junjie Hu, Qian Wang
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2016-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC4999272?pdf=render
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