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A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes.

Circumsporozoite protein (CSP) is the dominant protein on the surface of Plasmodium sporozoites and plays a critical role in the invasion by sporozoites of hepatocytes. Contacts between CSP and heparin sulfate proteoglycans (HSPGs) lead to the attachment of sporozoites to hepatocytes and trigger sig...

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Main Authors: Jinghua Zhao, Purnima Bhanot, Junjie Hu, Qian Wang
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science (PLoS) 2016-01-01
Sraith:PLoS ONE
Rochtain Ar Líne:http://europepmc.org/articles/PMC4999272?pdf=render
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