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A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes.

Circumsporozoite protein (CSP) is the dominant protein on the surface of Plasmodium sporozoites and plays a critical role in the invasion by sporozoites of hepatocytes. Contacts between CSP and heparin sulfate proteoglycans (HSPGs) lead to the attachment of sporozoites to hepatocytes and trigger sig...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jinghua Zhao, Purnima Bhanot, Junjie Hu, Qian Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2016-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC4999272?pdf=render
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