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Preclinical Models to Evaluate the Human Response to Autoantigen and Antigen-Specific Immunotherapy in Human Type 1 Diabetes

Type 1 Diabetes (T1D) is an autoimmune disease that results from the destruction of pancreatic islet β-cells by auto-reactive T cells. The clinical management of T1D faces the lack of fully predictive biomarkers in its preclinical stage and of antigen-specific therapies to induce or re-induce immune...

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Detalhes bibliográficos
Main Authors: Pamela Houeiss, Christian Boitard, Sandrine Luce
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Endocrinology
Assuntos:
HLA
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fendo.2022.883000/full
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