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T Cell Recognition of Autoantigens in Human Type 1 Diabetes: Clinical Perspectives
Type 1 diabetes (T1D) is an autoimmune disease driven by the activation of lymphocytes against pancreatic β-cells. Among β-cell autoantigens, preproinsulin has been ascribed a key role in the T1D process. The successive steps that control the activation of autoreactive lymphocytes have been extensiv...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140193/ https://ncbi.nlm.nih.gov/pubmed/21785617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/513210 |
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