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Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Tangle Formation, Amyloid-β, and Microglia in Alzheimer’s Disease

Pathological hallmarks of Alzheimer’s disease (AD) include senile plaques, neurofibrillary tangles (NFTs), synaptic loss, and neurodegeneration. Senile plaques are composed of amyloid-β (Aβ) and are surrounded by microglia, a primary immune effector cell in the central nervous system. NFTs are forme...

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Bibliografski detalji
Glavni autori: Kazuyuki Takata, Yoshihisa Kitamura
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2012-01-01
Serija:Journal of Pharmacological Sciences
Online pristup:http://www.sciencedirect.com/science/article/pii/S1347861319305584
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