Suppression of the Proliferation of Huh7 Hepatoma Cells Involving the Downregulation of Mutant p53 Protein and Inactivation of the STAT 3 Pathway with Ailanthoidol

Ailanthoidol (ATD) has been isolated from the barks of <i>Zanthoxylum ailanthoides</i> and displays anti-inflammatory, antioxidant, antiadipogenic, and antitumor promotion activities. Recently, we found that ATD suppressed TGF-β1-induced migration and invasion of HepG2 cells. In this rep...

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Main Authors: Tsui-Hwa Tseng, Chau-Jong Wang, Yean-Jang Lee, Yi-Chia Shao, Chien-Heng Shen, Ko-Chao Lee, Shui-Yi Tung, Hsing-Chun Kuo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-05-01
Colecção:International Journal of Molecular Sciences
Assuntos:
ailanthoidol
hepatoma
mutant <i>p53</i>
STAT3
apoptosis
cell cycle
Acesso em linha:https://www.mdpi.com/1422-0067/23/9/5102
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