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Characterization of increased drug metabolism activity in dimethyl sulfoxide (DMSO)-treated Huh7 hepatoma cells

1. The objective of this study was to characterize Huh7 cells' baseline capacity to metabolize drugs and to investigate whether the drug metabolism was enhanced upon treatment with dimethyl sulfoxide (DMSO). 2. The messenger RNA (mRNA) levels of major Phase I and Phase II enzymes were determine...

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Détails bibliographiques
Auteurs principaux: Choi, S., Sainz, B., Corcoran, P., Uprichard, S., Jeong, H.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953797/
https://ncbi.nlm.nih.gov/pubmed/19280519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498250802613620
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