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Optimizing human hepatocyte models for metabolic phenotype and function: effects of treatment with dimethyl sulfoxide (DMSO)

Primary human hepatocytes are considered to be the “gold standard” cellular model for studying hepatic fatty acid and glucose metabolism; however, they come with limitations. Although the HepG2 cell line retains many of the primary hepatocyte metabolic functions they have a malignant origin and low...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Physiol Rep
Prif Awduron: Nikolaou, Nikolaos, Green, Charlotte J., Gunn, Pippa J., Hodson, Leanne, Tomlinson, Jeremy W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5112488/
https://ncbi.nlm.nih.gov/pubmed/27803313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12944
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