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In vitro cellular models of human hepatic fatty acid metabolism: differences between Huh7 and HepG2 cell lines in human and fetal bovine culturing serum

Human primary hepatocytes are the gold standard for investigating lipid metabolism in nonalcoholic fatty liver disease (NAFLD); however, due to limitations including availability and donor variability, the hepatoma cell lines Huh7 and HepG2 are commonly used. Culturing these cell lines in human seru...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Gunn, Pippa J., Green, Charlotte J., Pramfalk, Camilla, Hodson, Leanne
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742701/
https://ncbi.nlm.nih.gov/pubmed/29263118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13532
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