SPAK Sensitive Regulation of the Epithelial Na+ Channel ENaC

Background/Aims: The WNK-dependent STE20/SPS1-related proline/alanine-rich kinase SPAK participates in the regulation of NaCl and Na+,K+,2Cl- cotransport and thus renal salt excretion. The present study explored whether SPAK has similarly the potential to regulate the epithelial Na+ channel (ENaC)....

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Main Authors: Musaab Ahmed, Madhuri S. Salker, Bernat Elvira, Anja T. Umbach, Hajar Fakhri, Amal M. Saeed, Ekaterina Shumilina, Zohreh Hosseinzadeh, Florian Lang
Formato: Artigo
Idioma:Inglês
Publicado em: Karger Publishers 2015-06-01
Colecção:Kidney & Blood Pressure Research
Assuntos:
Oocytes
Colon
Mice
WNK
Epithelial Na+ channels
Acesso em linha:http://www.karger.com/Article/FullText/368509
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