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Osmosensing, osmosignalling and inflammation: how intervertebral disc cells respond to altered osmolarity
Intervertebral disc (IVD) cells are naturally exposed to high osmolarity and complex mechanical loading, which drive microenvironmental osmotic changes. Age- and degeneration-induced degradation of the IVD’s extracellular matrix causes osmotic imbalance, which, together with an altered function of c...
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Autors principals: | , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
AO Research Institute Davos
2018-11-01
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Col·lecció: | European Cells & Materials |
Matèries: | |
Accés en línia: | http://www.ecmjournal.org/papers/vol036/pdf/v036a17.pdf |
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