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p38 MAPK Facilitates Crosstalk Between Endoplasmic Reticulum Stress and IL-6 Release in the Intervertebral Disc

Degenerative disc disease is associated with increased expression of pro-inflammatory cytokines in the intervertebral disc (IVD). However, it is not completely clear how inflammation arises in the IVD and which cellular compartments are involved in this process. Recently, the endoplasmic reticulum (...

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Vydáno v:Front Immunol
Hlavní autoři: Krupkova, Olga, Sadowska, Aleksandra, Kameda, Takuya, Hitzl, Wolfgang, Hausmann, Oliver Nic, Klasen, Juergen, Wuertz-Kozak, Karin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107791/
https://ncbi.nlm.nih.gov/pubmed/30174670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01706
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