RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

The development of cardiac dysfunction caused by microbial infection predicts high mortality in sepsis patients. Specialized pro-resolving mediators (SPMs) mediate resolution of inflammation in many inflammatory diseases, and are differentially expressed in plasma of sepsis patients. Here, we invest...

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Main Authors: Jianmin Chen, Gareth S. D. Purvis, Debora Collotta, Sura Al Zoubi, Michelle A. Sugimoto, Antonino Cacace, Lukas Martin, Roman A. Colas, Massimo Collino, Jesmond Dalli, Christoph Thiemermann
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2020-09-01
סדרה:Frontiers in Immunology
נושאים:
polymicrobial sepsis
resolvin E1
bacterial clearance
immune response
cardiomyopathy
גישה מקוונת:https://www.frontiersin.org/article/10.3389/fimmu.2020.02080/full
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