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Oxidative Homeostasis Regulates the Response to Reductive Endoplasmic Reticulum Stress through Translation Control

Reductive stress leads to the loss of disulfide bond formation and induces the unfolded protein response of the endoplasmic reticulum (UPRER), necessary to regain proteostasis in the compartment. Here we show that peroxide accumulation during reductive stress attenuates UPRER amplitude by altering t...

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Bibliografische gegevens
Hoofdauteurs: Shuvadeep Maity, Asher Rajkumar, Latika Matai, Ajay Bhat, Asmita Ghosh, Ganesh Agam, Simarjot Kaur, Niraj R. Bhatt, Arnab Mukhopadhyay, Shantanu Sengupta, Kausik Chakraborty
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2016-07-01
Reeks:Cell Reports
Online toegang:http://www.sciencedirect.com/science/article/pii/S2211124716307653
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