Oxidative Homeostasis Regulates the Response to Reductive Endoplasmic Reticulum Stress through Translation Control

Reductive stress leads to the loss of disulfide bond formation and induces the unfolded protein response of the endoplasmic reticulum (UPRER), necessary to regain proteostasis in the compartment. Here we show that peroxide accumulation during reductive stress attenuates UPRER amplitude by altering t...

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Autors principals: Shuvadeep Maity, Asher Rajkumar, Latika Matai, Ajay Bhat, Asmita Ghosh, Ganesh Agam, Simarjot Kaur, Niraj R. Bhatt, Arnab Mukhopadhyay, Shantanu Sengupta, Kausik Chakraborty
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016-07-01
Col·lecció:Cell Reports
Accés en línia:http://www.sciencedirect.com/science/article/pii/S2211124716307653
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