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Evaluation of efficiency and sensitivity of 1D and 2D sample pooling strategies for SARS-CoV-2 RT-qPCR screening purposes

Abstract To increase the throughput, lower the cost, and save scarce test reagents, laboratories can pool patient samples before SARS-CoV-2 RT-qPCR testing. While different sample pooling methods have been proposed and effectively implemented in some laboratories, no systematic and large-scale evalu...

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Autors principals: Jasper Verwilt, Jan Hellemans, Tom Sante, Pieter Mestdagh, Jo Vandesompele
Format: Artigo
Idioma:Inglês
Publicat: Nature Portfolio 2022-04-01
Col·lecció:Scientific Reports
Accés en línia:https://doi.org/10.1038/s41598-022-10581-6
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