Influence of point mutations on the stability, dimerization and oligomerization of human cystatin C and its L68Q variant

Human cystatin C (hCC) is a small but very intriguing protein. Produced by all nucleated cells is found in almost all tissues and body fluids where, at physiological conditions, plays a role of a very potent inhibitor of cysteine proteases. Biologically active hCC is a monomeric protein but during c...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Aneta eSzymanska, Elżbieta eJankowska, Marta eOrlikowska, Izabela eBehrendt, Paulina eCzaplewska, Sylwia eRodziewicz-Motowidło
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2012-07-01
Seri Bilgileri:Frontiers in Molecular Neuroscience
Konular:
Cystatin C
crystal structure
Oligomerization
stability
dimerization
mutants
Online Erişim:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00082/full
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller