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Structural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein
Wild-type human cystatin C (hCC wt) is a low-molecular-mass protein (120 amino-acid residues, 13 343 Da) that is found in all nucleated cells. Physiologically, it functions as a potent regulator of cysteine protease activity. While the biologically active hCC wt is a monomeric protein, all crystalli...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976269/ https://ncbi.nlm.nih.gov/pubmed/23519666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444912051657 |
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