Kynurenine Promotes RANKL–Induced Osteoclastogenesis In Vitro by Activating the Aryl Hydrocarbon Receptor Pathway

There is increasing evidence of the involvement of the tryptophan metabolite kynurenine (KYN) in disrupting osteogenesis and contributing to aging-related bone loss. Here, we show that KYN has an effect on bone resorption by increasing osteoclastogenesis. We have previously reported that in vivo tre...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Nada H. Eisa, Sakamuri V. Reddy, Ahmed M. Elmansi, Galina Kondrikova, Dmitry Kondrikov, Xing-Ming Shi, Chad M. Novince, Mark W. Hamrick, Meghan E. McGee-Lawrence, Carlos M. Isales, Sadanand Fulzele, William D. Hill
格式: Artigo
語言:Inglês
出版: MDPI AG 2020-10-01
叢編:International Journal of Molecular Sciences
主題:
Kynurenine
AhR
osteoclast
NFATc1
c-fos
在線閱讀:https://www.mdpi.com/1422-0067/21/21/7931
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍