Extensive Changes in Transcriptomic “Fingerprints” and Immunological Cells in the Large Organs of Patients Dying of Acute Septic Shock and Multiple Organ Failure Caused by Neisseria meningitidis

Background: Patients developing meningococcal septic shock reveal levels of Neisseria meningitidis (106-108/mL) and endotoxin (101-103 EU/mL) in the circulation and organs, leading to acute cardiovascular, pulmonary and renal failure, coagulopathy and a high case fatality rate within 24 h.Objective:...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Berit Sletbakk Brusletto, Else Marit Løberg, Bernt Christian Hellerud, Ingeborg Løstegaard Goverud, Jens Petter Berg, Ole Kristoffer Olstad, Unni Gopinathan, Petter Brandtzaeg, Reidun Øvstebø
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020-02-01
Schriftenreihe:Frontiers in Cellular and Infection Microbiology
Schlagworte:
FFPE
IHC
MOF
Neisseria meningitidis
septic shock
transcriptional profiles
Online Zugang:https://www.frontiersin.org/article/10.3389/fcimb.2020.00042/full
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge