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A case of acute promyelocytic leukemia variant with derivative chromosome 3 der(3)t(3;8) associated with 8q partial gain
Abstract Background Acute promyelocytic leukemia (APL) is characterized by fusion of PML/RARα genes as a result of t(15;17)(q24;q21). APL is now one of the curable hematological malignancies thanks to molecularly targeted therapies based on all-trans retinoic acid (ATRA) and arsenic trioxide (ATX)....
Tallennettuna:
Päätekijät: | , , , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
BMC
2019-07-01
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Sarja: | Molecular Cytogenetics |
Aiheet: | |
Linkit: | http://link.springer.com/article/10.1186/s13039-019-0445-1 |
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