Secondary Release of Exosomes from Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery after Stroke in Rats Treated with Exosomes Harvested from MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stromal Cells

We previously demonstrated that multipotent mesenchymal stromal cells (MSCs) that overexpress microRNA 133b (miR-133b) significantly improve functional recovery in rats subjected to middle cerebral artery occlusion (MCAO) compared with naive MSCs and that exosomes generated from naive MSCs mediate t...

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Hauptverfasser: Hongqi Xin Ph.D., Fengjie Wang, Yanfeng Li, Qing-E Lu, Wing Lee Cheung, Yi Zhang, Zheng Gang Zhang, Michael Chopp
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publishing 2017-02-01
Schriftenreihe:Cell Transplantation
Online Zugang:https://doi.org/10.3727/096368916X693031
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