Neurons and Astrocytes Elicit Brain Region Specific Transcriptional Responses to Prion Disease in the Murine CA1 and Thalamus

Progressive dysfunction and loss of neurons ultimately culminates in the symptoms and eventual fatality of prion disease, yet the pathways and mechanisms that lead to neuronal degeneration remain elusive. Here, we used RNAseq to profile transcriptional changes in microdissected CA1 and thalamus brai...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jessy A. Slota, Sarah J. Medina, Kathy L. Frost, Stephanie A. Booth
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Neuroscience
Assuntos:
prion
neurodegeneration
pathophysiology
synaptic dysfunction
neuroinflammation
reactive gliosis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fnins.2022.918811/full
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados