Early Mechanisms of Pathobiology Are Revealed by Transcriptional Temporal Dynamics in Hippocampal CA1 Neurons of Prion Infected Mice

Prion diseases typically have long pre-clinical incubation periods during which time the infectious prion particle and infectivity steadily propagate in the brain. Abnormal neuritic sprouting and synaptic deficits are apparent during pre-clinical disease, however, gross neuronal loss is not detected...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Majer, Anna, Medina, Sarah J., Niu, Yulian, Abrenica, Bernard, Manguiat, Kathy J., Frost, Kathy L., Philipson, Clark S., Sorensen, Debra L., Booth, Stephanie A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493483/
https://ncbi.nlm.nih.gov/pubmed/23144617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados