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Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes

BACKGROUND: Prion infection results in progressive neurodegeneration of the central nervous system invariably resulting in death. The pathological effects of prion diseases in the brain are morphologically well defined, such as gliosis, vacuolation, and the accumulation of disease-specific protease-...

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Detalhes bibliográficos
Main Authors: Sorensen, Garrett, Medina, Sarah, Parchaliuk, Debra, Phillipson, Clark, Robertson, Catherine, Booth, Stephanie A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2294129/
https://ncbi.nlm.nih.gov/pubmed/18315872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-114
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