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The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway.

The exosome and its nuclear specific subunit Rrp6 form a 3'-5' exonuclease complex that regulates diverse aspects of RNA biology including 3' end processing and degradation of a variety of noncoding RNAs (ncRNAs) and unstable transcripts. Known targets of the nuclear exosome include s...

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Detaylı Bibliyografya
Asıl Yazarlar: Melanie J Fox, Hongyu Gao, Whitney R Smith-Kinnaman, Yunlong Liu, Amber L Mosley
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2015-01-01
Seri Bilgileri:PLoS Genetics
Online Erişim:http://europepmc.org/articles/PMC4378619?pdf=render
Etiketler: Etiketle
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