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The Exosome Component Rrp6 Is Required for RNA Polymerase II Termination at Specific Targets of the Nrd1-Nab3 Pathway

The exosome and its nuclear specific subunit Rrp6 form a 3’-5’ exonuclease complex that regulates diverse aspects of RNA biology including 3’ end processing and degradation of a variety of noncoding RNAs (ncRNAs) and unstable transcripts. Known targets of the nuclear exosome include short (<1000...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Fox, Melanie J., Gao, Hongyu, Smith-Kinnaman, Whitney R., Liu, Yunlong, Mosley, Amber L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378619/
https://ncbi.nlm.nih.gov/pubmed/25680078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004999
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