The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice.

The ability of the Lentivirus HIV-1 to inhibit T-cell activation by its gp41 fusion protein is well documented, yet limited data exists regarding other viral fusion proteins. HIV-1 utilizes membrane binding region of gp41 to inhibit T-cell receptor (TCR) complex activation. Here we examined whether...

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Hlavní autoři: Etai Rotem, Omri Faingold, Meital Charni, Yoel A Klug, Daniel Harari, Liraz Shmuel-Galia, Alon Nudelman, Varda Rotter, Yechiel Shai
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2018-05-01
Edice:PLoS Pathogens
On-line přístup:http://europepmc.org/articles/PMC5955599?pdf=render
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