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An Immunomodulating Motif of the HIV-1 Fusion Protein Is Chirality-independent: IMPLICATIONS FOR ITS MODE OF ACTION

An immunosuppressive motif was recently found within the HIV-1 gp41 fusion protein (termed immunosuppressive loop-associated determinant core motif (ISLAD CM)). Peptides containing the motif interact with the T-cell receptor (TCR) complex; however, the mechanism by which the motif exerts its immunos...

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Detalhes bibliográficos
Main Authors: Faingold, Omri, Ashkenazi, Avraham, Kaushansky, Nathali, Ben-Nun, Avraham, Shai, Yechiel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829137/
https://ncbi.nlm.nih.gov/pubmed/24078631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512038
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