DQB1*06:02-Associated Pathogenic Anti-Myelin Autoimmunity in Multiple Sclerosis-Like Disease: Potential Function of DQB1*06:02 as a Disease-Predisposing Allele

Susceptibility to multiple sclerosis (MS) has been linked mainly to the HLA-DRB1 locus, with the HLA-DR15 haplotype (DRB1*1501-DQA1*0102-DQB1*0602-DRB5*0101) dominating MS risk in Caucasians. Although genes in the HLA-II region, particularly DRB1*1501, DQA1*0102-DQB1*0602, are in tight linkage diseq...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kaushansky, Nathali, Ben-Nun, Avraham
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4199271/
https://ncbi.nlm.nih.gov/pubmed/25360418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00280
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