Pregnancy-induced amelioration of muscular dystrophy phenotype in mdx mice via muscle membrane stabilization effect of glucocorticoid.

Duchenne muscular dystrophy (DMD), the most common and severe type of dystrophinopathy, is an X-linked recessive genetic disease caused by the absence of dystrophin, which leads to fragility and vulnerability of the sarcolemma to mechanical stretching with increased membrane permeability. Currently,...

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Hauptverfasser: Yuko Shimizu-Motohashi, Yoko Asakura, Norio Motohashi, Nandkishore R Belur, Michael G Baumrucker, Atsushi Asakura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2015-01-01
Schriftenreihe:PLoS ONE
Online Zugang:http://europepmc.org/articles/PMC4361742?pdf=render
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