Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disease in which the dystrophin coding for a membrane stabilizing protein is mutated. Recently, the vasculature has also shown to be perturbed in DMD and DMD model mdx mice. Recent DMD transcriptomics revealed the defects were correl...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Verma, Mayank, Shimizu-Motohashi, Yuko, Asakura, Yoko, Ennen, James P., Bosco, Jennifer, Zhou, Zhiwei, Fong, Guo-Hua, Josiah, Serene, Keefe, Dennis, Asakura, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6932757/
https://ncbi.nlm.nih.gov/pubmed/31877123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008468
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