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IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection.

Infection with the trematode parasite Schistosoma mansoni results in distinct heterogeneity of disease severity both in humans and in mice. In the experimental mouse model, severe disease is characterized by pronounced hepatic egg-induced granulomatous inflammation mediated by CD4 Th17 cells, wherea...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Patrick M Smith, Berri Jacque, James R Conner, Alexander Poltorak, Miguel J Stadecker
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2011-10-01
סדרה:PLoS Pathogens
גישה מקוונת:http://europepmc.org/articles/PMC3188523?pdf=render
תגים: הוספת תג
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