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IRAK-2 regulates IL-1-mediated pathogenic Th17 cell development in helminthic infection.
Infection with the trematode parasite Schistosoma mansoni results in distinct heterogeneity of disease severity both in humans and in mice. In the experimental mouse model, severe disease is characterized by pronounced hepatic egg-induced granulomatous inflammation mediated by CD4 Th17 cells, wherea...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2011-10-01
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| シリーズ: | PLoS Pathogens |
| オンライン･アクセス: | http://europepmc.org/articles/PMC3188523?pdf=render |
| タグ: |
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