α-type-1 polarized dendritic cell-based vaccination in recurrent high-grade glioma: a phase I clinical trial

<p>Abstract</p> <p>Background</p> <p>High-grade gliomas including glioblastoma multiforme (GBM) are among the most malignant and aggressive of tumors, and have a very poor prognosis despite a temozolomide-based intensive treatment. Therefore, a novel therapeutic approac...

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Main Authors: Akiyama Yasuto, Oshita Chie, Kume Akiko, Iizuka Akira, Miyata Haruo, Komiyama Masaru, Ashizawa Tadashi, Yagoto Mika, Abe Yoshiaki, Mitsuya Koichi, Watanabe Reiko, Sugino Takashi, Yamaguchi Ken, Nakasu Yoko
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-12-01
Colecção:BMC Cancer
Assuntos:
Dendritic cell
Immunotherapy
High-grade glioma
HLA-A24
Phase I trial
Acesso em linha:http://www.biomedcentral.com/1471-2407/12/623
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